Harshal Deshmukh, United Kingdom

University of Hull Academic Diabetes and Endocrinology

Presenter of 1 Presentation

ORAL PRESENTATION SESSION

FACTORS ASSOCIATED WITH IMPROVEMENT IN DIABETES-RELATED DISTRESS IN PEOPLE LIVING WITH TYPE 1 DIABETES WITH FREESTYLE LIBRE -ASSOCIATION OF BRITISH CLINICAL DIABETOLOGISTS (ABCD) STUDY

Abstract

Background and Aims

We have recently shown that use of FSL is associated with improvement in diabetes-related distress (DDS) in people with T1D. The objective of this study was to identify factors associated with improvement in DDS following the use of FSL.

Methods

The study was performed using data from the ABCD nationwide FreeStyle Libre audit. We collected diabetes-related distress scores at baseline and follow up (two-item diabetes distress screening instrument, ‘feeling overwhelmed by the demands of living with diabetes’ and ‘feeling that I am often failing with my diabetes routine’DDS2). An average item score of ≥3 (moderate distress) discriminated high from low-distressed subgroups. We used an unsupervised gradient boosting machine learning model (GBM) to identify the relative influence (RI) of post-FSL use on two components of DDS. Since the two components were correlated, we only present the factors associated with the change in DDS1 following FSL use.

Results

The study included 4,588 people living with T1D who had baseline and post-FSL DDS score and consisted of 48.6% female, with baseline, and post FSL HbA1c of 67.6(±16.02)) and 62.9 (±14.02) mmol/l and a baseline and post FSL DDS of 2.8(±1.4) and 2.2(±1.9) respectively. In the GBM model, improvement in the GOLD score (RI=42.2), and HbA1c with FSL use (RI=19.4), post-FSL HbA1c (RI=13.8) and the greater number of FSL scans per day (RI=10.07) were associated post FSL reduction in DDS.

Conclusions

Improvement in hypoglycaemia awareness, glycaemic control and engagement with FSL is associated with improved DDS in people living with T1D.

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