Venugopal Vijayakumar, India
Government Yoga and Naturopathy Medical College & Hospital Department of YogaPresenter of 1 Presentation
EFFECT OF YOGA ON REDUCING GLYCEMIC VARIABILITY IN INDIVIDUALS WITH TYPE 2 DIABETES: A RANDOMISED CONTROLLED TRIAL
Abstract
Background and Aims
Glycemic variability is a known risk factor for cardiovascular complications in type 2 diabetes mellitus (T2DM). Yoga is a moderate intensity physical activity and is considered to be beneficial for patients with T2DM. The objective of the current study is to understand the effect of yoga on glycemic variability.
Methods
Individuals with T2DM (n=60) of both genders, 40-70 years of age, HbA1C between 7% - 8.5% were recruited from a tertiary referral centre for diabetes. Subjects were randomly assigned to either intervention (yoga) or control (brisk walking) group. During the first 7 days, baseline glycemic variability was established using Freestyle Libre pro flash glucose monitoring system, followed by 7 days of either one hour of yoga or walking per day. A traditional validated yoga module was taught. Data on glycemic variability was obtained on baseline, day 7 and 14.
Results
In total, 57 participants successfully completed the study. Mean reduction in daily average glucose level was higher in intervention groups than control group (23.99±18.78 vs 8.69±27.08 mg/dL), with no significant difference between groups (p>0.05). However, significant reduction in various measures of glycemic variability was observed in intervention group (SD: 9.79 ±7.56 vs 4.67 ±7.13; MAGE: 17.47 ±21.25 vs 6.15 ±13.6; % CV: 3.33 ±4.09 vs1.03 ±2.98; MODD: 8.38 ±6.18 vs 1.16 ±8.08) when compared to the control group (p < 0.001).
Conclusions
Short term yoga practice has shown a statistically significant reduction in the glycemic variability in T2DM when compared to brisk walking, inspite of a similar reduction in mean blood glucose levels.