Background and Aims

There is only few study FGM in pregnant woman with T1DM.

Aim. Compare FGM with SMBG and CGM in pregnant woman with T1DM.

Methods

31years-old woman with T1DM, 9ws of pregnancy. HbA1c 5,4%. SMBG(AccuCheck Performa), FGM(FreeStyleLybre) and CGM(iPro) was performed. We aligned each glucose value of SMBG with the closest glucose value FGM and CGM. 109pairs of SMBG with FGM/CGM and 739pairs of FGM and CGM was obtained.

Results

Mean glucose value of FGM was significantly lower than CGM and SMBG (4,9±2,1mmol/l; 5,8±2,2mmol/l and 6,3±2,4mmol/l accordingly, p=0,001). MAD between FGM and SMBG values was slightly more than between CGM and SMBG: 1,2±0,9mmol/l&0,9±1,4mmol/l, р=0,09. MARD between groups were significantly different, p=0,009. CGM showed better accuracy than FGM: MARD between CGM and SMBG was 13,9±13,4%, between FGM and SMBG 20,8±13,8%, p<0,001. MARD was the worst in the 1^stday: 39,4±12,4% between FGM and SMBG, 33,8±16,8% between CGM and SMBG. Without 1^stday MARD decreases: 20,7±13,7% in the pairs of FGM and SMBG, 11,5±9,2% in the pairs of CGM and SMBG, p<0,001. Consensus Error Grid analysis demonstrated 89,9%values of CGM and 88,1%values of FGM in zone A and B. 74,3%results of CGM and 58,7%results of FGM were in zone A, p=0,03. Most the results in zone C were on the f1^stday. The Pearson correlation with SMBG was high: 0,918 for FGM and 0,911 for CGM.

Conclusions

FGM shows as high correlation with SMBG as CGM. Error results were often on the 1^stday sensor inserting. About 90%results of FGM were in zone A and B so its clinically acceptable.