THE INTRODUCTION OF MINIMED 670G HYBRID CLOSED LOOP INSULIN PUMP AUTO MODE SYSTEM IMPROVES GLYCAEMIC CONTROL IN ROUTINE CLINICAL PRACTICE

Session Name
INSULIN PUMPS
Session Type
E-POSTER VIEWING (EXHIBITION HOURS)
Date
20.02.2020, Thursday
Session Time
09:30 - 15:30
Channel
E-Poster Area
Lecture Time
10:03 - 10:04
Presenter
  • Ales Skvarca, Slovenia
Authors
  • Ales Skvarca, Slovenia

Abstract

Background and Aims

Good glycaemic control is often difficult to achieve in patients with type 1 diabetes mellitus (T1DM), especially without increasing time spent in hypoglycaemia. Recently, MiniMed 670G hybrid closed loop insulin pump system has been introduced into clinical practice. The aim of this analysis was to evaluate the effect of MiniMed 670G Auto Mode (AM) on the glycaemic control in the first 12 weeks after AM initiation in routine clinical practice.

Methods

Twelve T1DM patients (aged 42.0±15.6 years, duration of diabetes 27.5±15.9 years) using Medtronic MiniMed 670G hybrid insulin pump and continuous glucose monitoring (CGM) system were included in the analysis. HbA1c level was measured at baseline and after 12 weeks. The CGM data of the preceding two weeks were analysed at the time of the AM initiation and after 12 weeks of treatment. Several parameters were determined and analysed: time in range (TIR; % of readings 3.9-10.0 mmol/l), time above range (TAR; % of readings >10.0 mmol/l), time below range (TBR; % of readings <3.9 mmol/l) and time in AM.

Results

Twelve weeks after AM initiation HbA1c level significantly decreased from 7.8±0.8% to 7.1±0.6 (p=0.002). TIR increased from 69.4±7.5 to 71.8±7.6 % (NS). TAR increased only slightly from 26.5±8.0 to 26.7±7.8 % (NS). TBR significantly decreased from 4.1±4.5 to 1.5±1.0 (p=0.04). Average percentage of time in AM after twelve weeks was 89.2±9.1 %.

Conclusions

The introduction of MiniMed 670G hybrid closed loop insulin pump AM system quickly improves overall glycaemic control and decreases time spent in hypoglycaemia, without increasing time spent in hyperglycaemia.

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