THE EFFECT OF AGE ON GLYCEMIC OUTCOMES IN A LARGE COHORT OF EVERSENSE CGM SYSTEM ADULT USERS

Session Type
ORAL PRESENTATION SESSION
Date
22.02.2020, Saturday
Session Time
10:30 - 12:00
Channel
La Paz
Lecture Time
11:10 - 11:20
Presenter
  • Katherine S. Tweden, United States of America
Authors
  • Katherine S. Tweden, United States of America
  • Patricia Sanchez, United States of America
  • Samanwoy Ghosh-dastidar, United States of America
  • Francine Kaufman, United States of America

Abstract

Background and Aims

Accuracy and safety of the implantable Eversense CGM system, approved by the FDA in 2018, have been demonstrated in multiple clinical trials and real-world analyses. No glucometric outcomes by age have been reported.

Methods

Anonymized sensor glucose (SG) data from Eversense data management system (DMS) were analyzed for the first 582 patients with a 90‐day wear period. Mean SG, GMI, and percent time across glucose ranges were calculated for various age ranges from young adult to Medicare-age populations.

Results

Among 582 patients, ~85 identified as TID, and ~1/3 reported being CGM naïve. Percent of time in various ranges demonstrated time in range (TIR, 70-180 mg/dL), time below ranges (<70 mg/dL and <54 mg/dL), and time above ranges (>180 mg/dL and >250 mg/dL) improved with age, with a 50% TIR in patients 18-24 years of age to 68% and 70% TIR in patients >60 and ≥65 years of age, respectively (Table). Mean GMI and SG also decreased with age. Hypoglycemia did not increase with age.

Conclusions

These data demonstrated that glycemic outcomes improve with age in Eversense CGM system users. The older, Medicare cohort did not have an increase in hypoglycemia compared to other adult groups, despite the lowest GMI and highest TIR. While glucometrics in young adults are not optimal, these results (in a small cohort) suggest that a long-term implantable sensor might offer this age group the opportunity to attain A1C results, as supported by GMI data, less than 8% with an acceptable risk of hypoglycemia. age on glycemic outcomes.png

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