Insulin infusion pump therapy (IIPT) is the treatment of choice for the treatment of type 1 diabetes mellitus (type 1 DM), especially in patients under five years of age. The aim of this study was to compare the effects of IIPT and multidose insulin therapy (MDT) at the time of diagnosis in children with Type 1 DM on anthropometric measurements, HbA1c, daily insulin requirement and basal-bolus rates.
10 patients with Type 1 DM who were followed by IIPT at the time of diagnosis and followed up regularly for at least 1 year, and 10 patients with Type 1 DM using MDT, who were similar in terms of age and sex, were included in the study . Daily total insulin (U / kg) requirement, daily basal and bolus insulin rates and HbA1c values of the patients were compared.
The mean age at diagnosis was 2.01 ± 1.28 years in the IIPT group and 3.11 ± 1.49 years in the MDT group . HbA1c values measured in the first year showed a significant decrease in both treatment groups, whereas HbA1c values were significantly lower in the IIPT group compared to the MDT group. In the IIPT group, the mean daily total insulin requirement was lower than MDT group.
It has been shown that in patients with Type 1 DM who use IIPT at the time of diagnosis, 1-year follow-up provides better metabolic control with lower daily insulin dose compared to those using MDT. Long-term studies with more patients are needed.