LIPOATROPHIC DIABETES: A TYPE OF DIABETES DIFFICULT TO MANAGE IN TUNISIA

Session Name
NEW MEDICATIONS FOR TREATMENT OF DIABETES
Session Type
E-POSTER VIEWING (EXHIBITION HOURS)
Date
20.02.2020, Thursday
Session Time
09:30 - 15:30
Channel
E-Poster Area
Lecture Time
09:47 - 09:48
Presenter
  • Chaima Jemai, Tunisia
Authors
  • Chaima Jemai, Tunisia
  • Hajer Kandara, Tunisia
  • Mahdi Kalthoum, Tunisia
  • Manel Jmal, Tunisia
  • Ines Kammoun, Tunisia

Abstract

Background and Aims

Lipoatrophic diabetes is an exceptional form of diabetes mellitus. His current care in Tunisia is difficult.

Methods

We report the case of a patient with lipoatrophic diabetes associated with schizophrenia.

Results

This is a 28-year-old patient hospitalized for ketotic decompensation of her diabetes. She comes from a consanguineous marriage of second degree, diabetic from then 5 years, with the antecedents of acute pancreatitis with repetition and schizophrenia since two years. No other pathological history, including no antiretroviral therapy. The clinical examination shows a BMI of 22.03 kg / m², a whole height of 95 cm, with partial lipoatrophy that would be installed since adolescence characterized by slender limbs and fat accumulation at the abdominothoracic level, hypertrophy bilateral parotid, acanthosis nigricans, smooth lower hepatomegaly with normal liver function and hepatic steatosis on ultrasound. no associated muscular atrophy. Diabetes is poorly balanced with 13.9% HbA1C complicated with diabetic retinopathy, with insulin requirements of 2 IU / kg / d. The lipidogram shows a hepertriglyceridemia at 16 mmol / L with a fasting opalescent serum. The thyroid status is normal.

Conclusions

Lipoatrophic diabetes is an exceptional entity that is difficult to manage because of the severity of insulin resistance and the lack of standardized therapeutic management. Our patient is a real case with difficulty equilibrium of diabetes despite the increase in doses of insulin, the only available therapy in Tunisia in this case. New therapies must be offered to these patients to balance diabetes and prevent complications.

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