NEW ATTEMPT IN PREVENTION OF INSULIN INDUCED LIPOHYPERTROPHY IN DIABETIC PATIENTS

Session Name
ADVANCED MEDICAL TECHNOLOGIES TO BE USED IN HOSPITALS
Session Type
E-POSTER VIEWING (EXHIBITION HOURS)
Date
20.02.2020, Thursday
Session Time
09:30 - 15:30
Channel
E-Poster Area
Lecture Time
09:46 - 09:47
Presenter
  • Natalya Volkova, Russian Federation
Authors
  • Ilya Davidenko, Russian Federation
  • Natalya Volkova, Russian Federation

Abstract

Background and Aims

Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by subcutaneous injections of insulin. Nowadays, on the basis of results of ultrasonography of subcutaneous fat prevalence of LH in diabetic patients is still high. The aim has been to develop prevention of insulin induced LH in diabetic patients.

Methods

This study was done on 140 diabetic patients on insulin therapy a mean 8 years. On first stage patients were divided into two groups. First–117 patients with LH, second–23 diabetics without LH. All known LH risk factors were statistically processed using Spearman rank correlation coefficients. Results were statistically significant when p<0,05. On second stage 65 patients from first group were divided into two subgroups. First–50 patients with LH and corrected risk factors, second (control)–15 diabetics with LH and uncorrected risk factors. Ultrasonography were used in assessing new LH in these subgroups after 3 and 6 month.

Results

10 factors were remained after statistic analysis on first stage (p>0,05). Further, in first subgroup only 2 patients (4%) had new LH, while in second–9 diabetics (60%) had new pathologic areas of subcutaneous fat after 3 month. And in first subgroup only 6 patients (12%) had new pathologic areas of subcutaneous fat, while in second–12 diabetics (80%) had new LH after 6 month.

Conclusions

There were stated that only 10 risk factors strongly influence on LH progress. Correction of these risk factors doesn`t lead to development of new subcutaneous fat pathological changes and could be used to prevent LH in diabetic patients in clinical daily practice.

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