Aim of this study was to identify antioxidant and anticancer compounds present in the C. viminalis leaves extracts and its anticancer activity against liver cancer cell lines by inhibiting STAT3 protein.
The free radical scavenging potential of various extract of C. viminalis leaves were determined by the DPPH, superoxide anion radical scavenging, hydrogen peroxide scavenging, nitric oxide scavenging and reducing power assay. The anticancer activity of C. viminalis leaves extracts have been evaluated against human embryonic kidney (HEK-293) cell line, human liver cancer (HepG-2) and breast cancer (MCF-7) cell lines. The chemical composition of C. viminalis is analyzed by gas chromatography/mass spectrometry (GC-MS).
The results were revealed that ELE and MLE extracts of
The ELE and MLE extracts reduces the cell proliferation against liver cancer cell lines by inhibiting of STAT3 protein and can be successfully exploited in the herbal formulation of cancer chemoprevention and chemotherapy.
Jamia Millia Islamia
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All authors have declared no conflicts of interest.