While HIV responses worldwide urgently need to revitalize their focus on the HIV prevention, diagnosis and treatment needs of key populations, the broader health needs of key populations also need to be recognized and addressed. Key population health needs extend to ensuring access to appropriate services for viral hepatitis and sexually transmitted infections (STIs) along with a broader package that includes mental health, transition care, substance use and sexual and reproductive health services. This session will explore new and emerging World Health Organization recommendations related to key populations across HIV, viral hepatitis, STIs and broader health. It will discuss the latest evidence and programmatic examples of providing person centered services to key populations in different settings through integrated services, service delivery, programming and funding that harnesses the synergies between the three diseases as well as broader health.