The global UNAIDS target is 3 million active PrEP users by the end of 2020 but as of June there were only an estimated 575,000 enrolled. Despite slow roll-out initially, there are now at least 78 countries offering PrEP but with less diversity in service models than seen in differentiated ART delivery. Pre-COVID-19, there was a move towards more community-based or virtual/Telehealth models that have since been accelerated during COVID-19 country lock-downs. In this session, we will highlight how some countries have rapidly pivoted PrEP programming be more differentiated and truly client-centered—offering online, community, and private-sector service options to expand and maintain access. In the live session, perspectives from providers, PrEP users, ministry of health, and global normative agencies will also be shared with a moderated discussion on how a differentiated approach to PrEP will be essential to significantly increase uptake by the end of 2020 and beyond!