Dr Morvane Colin, is the leader of ‘Tau spreading’ group in the ‘Alzheimer & Tauopathies’ team headed by Luc Buée (Lille Neuroscience & Cognition, France). She is Associate Professor in Cell Biology from 2005 at the University of Lille. She firstly acquired expertise in viral vectors and their genome engineering in oncology and from 2010 in neurology. Hence, she joined Luc Buée’s team to develop in vivo and in vitro models of tau pathology spreading. She coordinates one assistant professors, two to four engineers, phD/PostDoc students & master students. She is focussing on tau spreading and especially the cellular mechanism supporting this process (ie extracellular vesicles, free tau…etc). Thanks to animal and cell models she developed to follow tau spreading, immunotherapeutic approaches in collaboration with industrial partners from 2015 was initiated (UCB Biopharma, Belgium). Cell models and new tools (microfluidics, multielectrode arrays…) are also upgraded to follows cell-to-cell transfer mechanisms. She is also working in closed collaboration with the hospital (MMRC, ‘Lille Resources and Research Memory Centre, Prs Pasquier & Deramecourt) to move to human samples to better characterized the spreading process and finally define better therapeutic targets. She gets regular funding to supports her personal scientific projets.