Women's Brain Project
Chief Scientific Officer
Maria Teresa is a neuroscientist with over 10-year international research experience and a unique expertise in gender medicine. After a master in Pharmacy (University of Cagliari, Italy) and a stage at the Center of Excellence for Drug Discovery of GlaxoSmith&Kline (Harlow, England), she obtained a PhD in Pharmacology at McGill University (Montreal, Canada) with a thesis on the role of inflammation in Alzheimer’s Disease. In 2011 she joined the Nitsch’s lab (University of Zurich, Switzerland) as postdoc and group leader, to further study the role of the immune system in Alzheimer’s using deep-immunophenotyping techniques. In 2016 Maria Teresa co-founded the non-profit organization ‘Women’s Brain Project’, which studies sex and gender determinants to brain and mental health as gateway to precision medicine (www.womensbrainproject.com). Her work as WBP Chief Scientific Officer led to several scientific publications, policy papers, books and book chapters, TED-x talks and coverage by the national and the international press. Maria Teresa is also an external teacher at the Medical University of Vienna (Austria), faculty member of the Certificate for Advance studies on gender medicine at University of Zurich and member of the Advisory Board of the Connors Center at the Women’s and Brigham’s Hospital in Boston. In 2021, with Dr Santuccione, she co-authored the book ‘Una bambina senza testa’ (Edizioni Mondo Nuovo).

Moderator of 1 Session

Session Type
SYMPOSIUM
Date
Sun, 20.03.2022
Session Time
11:35 AM - 01:35 PM
Room
ONSITE: 113

Presenter of 2 Presentations

Up for debate: Challenging topics in AD

Session Type
PRE CONFERENCE SYMPOSIUM
Date
Tue, 15.03.2022
Session Time
12:30 PM - 05:30 PM
Room
ONSITE: 112
Lecture Time
03:15 PM - 04:15 PM

SEX AND GENDER CONSIDERATIONS IN NEURODEGENERATIVE DISEASES: SCIENTIFIC EVIDENCE, BIASES, AND OPPORTUNITIES FOR PRECISION MEDICINE

Session Type
SYMPOSIUM
Date
Sun, 20.03.2022
Session Time
11:35 AM - 01:35 PM
Room
ONSITE: 113
Lecture Time
12:05 PM - 12:20 PM

Abstract

Abstract Body

Cumulating evidence has indicated high degree of patient variability in neurodegenerative disorders. Precision medicine, as already in use in oncology, might provide substantial progress in the field, from molecular diagnosis to tailored treatments.

In this regard, sex and gender differences are emerging as leading features driving patient heterogeneity in a variety of brain diseases, including Alzheimer. These differences offer therefore a useful starting point to discuss potential applications of precision medicine in neurology.
Taking the example of Alzheimer’s and Parkinson Disease, in this talk I will discuss the role of sex and gender differences in biomarker research, clinical trial design and development of digital health technologies, highlighting the work that the non-profit organization Women's Brain Project is doing in this field.

A proper understanding of sex and gender-differences will be key towards a precision medicine paradigm for neurodegenerative diseases, beyond a ‘one size fits all’ approach and towards sustainability.

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