Moderator of 1 Session
Presenter of 2 Presentations
Up for debate: Challenging topics in AD
SEX AND GENDER CONSIDERATIONS IN NEURODEGENERATIVE DISEASES: SCIENTIFIC EVIDENCE, BIASES, AND OPPORTUNITIES FOR PRECISION MEDICINE
Abstract
Abstract Body
Cumulating evidence has indicated high degree of patient variability in neurodegenerative disorders. Precision medicine, as already in use in oncology, might provide substantial progress in the field, from molecular diagnosis to tailored treatments.
In this regard, sex and gender differences are emerging as leading features driving patient heterogeneity in a variety of brain diseases, including Alzheimer. These differences offer therefore a useful starting point to discuss potential applications of precision medicine in neurology.
Taking the example of Alzheimer’s and Parkinson Disease, in this talk I will discuss the role of sex and gender differences in biomarker research, clinical trial design and development of digital health technologies, highlighting the work that the non-profit organization Women's Brain Project is doing in this field.
A proper understanding of sex and gender-differences will be key towards a precision medicine paradigm for neurodegenerative diseases, beyond a ‘one size fits all’ approach and towards sustainability.