P786 - PROGRESS IN ONE YEAR OF AUTOBIOGRAPHICAL MEMORY IN ALZHEIMER’S DISEASE (ID 1852)
Abstract
Aims
Autobiographical memory consists of a person’s personal history and contributes to building a feeling of identity and continuity. Detecting changes in Alzheimer's disease in the early stages is one of the main challenges of current research. Autobiographical memory involves the retention and retrieval of experiences from one’s personal past. For this reason, it is important to know the changes that occur in autobiographical memory during Alzheimer's disease. This study evaluated semantic and episodic autobiographical memory in Alzheimer's disease patients and compared their scores within one year to analyze possible differences.
Methods
Methods: Autobiographical Memory Interview was applied to 14 patients with Alzheimer's disease. Autobiographical Memory Interview is a semi-structured interview used to assess memory retrieval in two domains: personal semantic and autobiographical incidents that are considered episodic. Paired-Samples T Test were applied.
Results
Autobiographical Memory scores of the participants who were assessed one year apart were compared. The analysis of means showed differences for semantic autobiographical memory (p = .012; Xpre = 39, Xpost = 31.5) with a significant decrease; episodic autobiographical memory also showed a significant decrease in the means obtained p = .008; Xpre = 11.7, Xpost = 7.6).
Conclusions
In patients with Alzheimer’s disease, a significant deterioration is observed in both semantic and episodic autobiographical memory.
