Dr. Dmitriy Yablonskiy is a Professor at the Washington University School of Medicine Radiology Department. Hi is a physicist with more than 25-year experience in developing theoretical biophysical models of biological tissue structure and functioning that are used as foundations for designing new quantitative MRI-based methods for in vivo studying of humans and animals in health and disease. He has authored and co-authored more than 200 papers in peer-review journals in the areas of MRI, physiology, and theoretical physics. Dr. Yablonskiy recent work is focused on applying MRI-based Gradient Echo Plural Contrast Imaging (GEPCI) and its advanced version quantitative Gradient Recalled Echo (qGRE) techniques that his lab has developed to link brain genetic and cellular microstructure with brain functioning in health and diseases, including Alzheimer disease and multiple sclerosis. In Alzheimer disease, qGRE identifies tissue cellular damage well-before onset of the tissue atrophy measured by volumetric MRI, thus allowing early diagnostic of the preclinical asymptomatic stage of Alzheimer disease and providing a large window for screening population for preclinical AD pathology and clinical drug trials. Similar, in multiple sclerosis, qGRE uncovers brain tissue damage in normal appearing gray matter and white matter that is not visible with standard clinical MRI.