Asad Jan (Denmark)

Aarhus University Department of Biomedicine
I completed professional studies in Clinical Medicine and obtained PhD in Neuroscience. During my academic tenures, I have provided scientific leadership and project management in research studies applied to age related neurological diseases, in particular Alzheimer disease (AD) and Parkinson disease (PD). In close collaboration with several international teams- often involving academic and clinical (pathologists, oncologists, and neurologists) researchers, my research work has contributed to novel insights into the pathogenic mechanism in brain pathologies, in particular disrupted regulation of mRNA translation (via eEF2 kinase) and impaired redox regulation (e.g., Nrf2 anti-oxidant response). These studies encompass cellular and animal models, rigorous histopathological analyses of human post-mortem tissue specimen, and through validation in patient-derived microarray gene expression datasets.