Session Description:

This symposium will focus on recent neurophysiological findings in Alzheimer’s disease, and their application for predicting disease progression and potential therapeutic benefits of treatments. Professor Javitt will summarize their latest results on amyloid pathology contributing to disrupted visual processing. Professor Arakaki will discuss how amyloid and tau pathologies impair the brain’s gamma oscillations related to cognitive processing. Dr. Cimenser will present recent findings from Cognito Therapeutics, demonstrating that degree of coherence in sensory evoked oscillations predict clinical outcomes of the therapy. The overall aim of the symposium is to highlight how neurophysiology can facilitate a greater understanding Alzheimer’s disease pathology and treatment.