CLINICAL SPECTRUM OF NEUROLOGICAL COMPLAINT IN COVID-19 : EXPERIENCES FROM COVID-19 REFERRAL HOSPITAL IN INDONESIA REVIEW OF CLINICAL, RADIOLOGICAL, AND LABORATORY FINDINGS

Session Type
SYMPOSIUM
Date
10.03.2021, Wednesday
Session Time
08:00 - 09:45
Room
On Demand Symposia A
Lecture Time
09:00 - 09:15
Presenter
  • Rocksy F. Situmeang, Indonesia
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On-Demand

Abstract

Aims

To identify clinical, radiological, and laboratory findings in COVID-19 patients who complain of neurological symptoms.

Methods

This study was a retrospective observational study conducted at Siloam Mampang Hospital, a COVID-19 referral hospital in South Jakarta, DKI Jakarta. We analyzed medical records of COVID-19 patients confirmed by real-time reverse transcriptase polymerase-chain-reaction (rt-PCR) from nasopharyngeal samples during the April - July 2020. The data collected were demographic data, comorbid conditions, neurological manifestations, laboratory examinations, and neuro-imaging.

Results

During April - July 2020, there were 22 confirmed COVID-19 patients with neurological complaint. The mean age of the patients was 60.4 (SD 15.8) years old.The most commoncomplained neurological symptom were altered mental status (50%), hemiparesis (27.3%), and tremor (22.7%). More than half of the patients (81.8%) had a comorbid condition or past history related to neurological symptoms. Laboratory examination results showed increased NLR (neutrophil-lymphocyte ratio)(50%), anemia (45.5%), and leukocytosis (40.1%). The most common neuroimaging feature was ischemic / infarct (50%).

Conclusions

The neurological complaints in COVID-19 patients may be caused by exacerbation of pre-existing comorbidities due to the severe inflammatory process triggered by COVID-19. More research is needed to confirm the mechanism of nervous system damage in COVID-19.

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